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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionMuscle protein synthesis window — September 2026 Page 3

Muscle protein synthesis window — September 2026

VanRx_Mike Sun, Aug 4, 2024 at 11:18 AM 11 replies 1,821 viewsPage 3 of 3
Dr.KarenChen
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Aug 4, 2024 at 8:52 PM#11
Dr.BariatricHTX said:
The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0…

Agreed on the ranges, with the condition that a single DEXA is not a measurement, it is one draw from a distribution. Hydration status moves the lean compartment by a kilogram or more between scans, so any comparison of scans done at different times of day or different hydration states is noise.

33 6julia.endo, JessicaM_2024, TomFromTexas and 30 others
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Dr.PathRoch
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Aug 5, 2024 at 12:31 AM#12
Dr.EM_Chicago said:
Agreed on the target, with the caveat that reference weight and current weight are different numbers.

This is exactly what I could not find anywhere else. Adding it to my notes with a link back to this thread.

Last edited: Aug 5, 2024 at 6:31 AM
34 7InsuranceTom, WendyG_ATL, SaraMom3 and 31 others
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JessicaM_2024
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Aug 5, 2024 at 4:09 AM#13
Dr.BariatricHTX said:
The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0…

Pushing back on Dr.BariatricHTX here. I think this board over-worries about lean mass. Some lean loss is obligatory — you need less muscle to move a smaller body, and preserving mass you no longer need is not a health outcome. The question is whether strength and function held, and mine did.

35 8mike_mealprep, NicoleRaleigh, james_edin and 32 others
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DoseLogDan
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Aug 5, 2024 at 7:47 AM#14

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Last edited: Aug 5, 2024 at 8:47 AM
36 9sophie_paris, mel_PDX, Dr.AddMedPHL and 33 others
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Admin
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Aug 5, 2024 at 11:25 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. No action needed from anybody.

Last edited: Aug 5, 2024 at 3:25 PM
37 10PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 34 others
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