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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsHas anyone dealt with [premium] from morbid obesity to marathon finisher? Page 3

Has anyone dealt with [premium] from morbid obesity to marathon finisher?

mike.trainer_LA Wed, Sep 10, 2025 at 4:10 AM 26 replies 1,412 viewsPage 3 of 6
MariaRD
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Sep 10, 2025 at 3:36 PM#11
PharmacoVig_BOS said:
Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body.

This is exactly what I could not find anywhere else.

Last edited: Sep 10, 2025 at 4:36 PM
31 4Dr.NutriCornell, pam_stl, wei_SG and 28 others
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claudia_zurich
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Sep 10, 2025 at 6:42 PM#12

From the other side of the consultation, briefly. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

32 5tammy_FL, Dr.LipidDallas, alex_tucson and 29 others
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kate.chem
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Sep 10, 2025 at 9:48 PM#13
james_edin said:
The useful move here is to separate what is established from what is widely repeated.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

33 6tyler_CSCS, VanRx_Mike, steve_okc and 30 others
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raj_cambridge
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Sep 11, 2025 at 12:53 AM#14

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: Sep 11, 2025 at 1:53 AM
34 7PharmHunterJen, TomTeleRx, DoseLogDan and 31 others
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Admin
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Sep 11, 2025 at 3:58 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Report rather than reply if it drifts again.

35 8PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 32 others
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