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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with moisture content analysis for lyophilized peptides? Page 6

Has anyone dealt with moisture content analysis for lyophilized peptides?

newstart_MO Thu, May 30, 2024 at 8:42 AM 54 replies 2,788 viewsPage 6 of 11
MarkLI_maint
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Aug 28, 2024 at 5:02 AM#26
SleepDoc_PDX said:
Say what you would expect to see if you were wrong, before you look.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Correct me if the detail matters more than I have assumed.

14 12RunnerRach, TrialNerd_Beth, HPLC_Greg and 11 others
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TrialTracker_MD
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Sep 9, 2024 at 1:00 AM#27
SleepDoc_PDX said:
Say what you would expect to see if you were wrong, before you look.

Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.

15 13stefan_berlin, Dr.EM_Chicago, pete_RVA and 12 others
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rachel_ABQ
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Sep 20, 2024 at 8:51 PM#28

From the other side of the consultation, briefly. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

16 14AmyNC_wife, SkepticalSean, Dr.CardioMD and 13 others
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Sigma-Aldrich — Research-Grade Standards

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hyun_seoul
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Seoul, KR
Oct 2, 2024 at 4:35 PM#29
rachel_ABQ said:
The version of this that has an answer is narrower than the version being asked.

Same pattern here, and in the same order.

17 15BariatricNurseD, MASHdoc_SA, GenomicsKate and 14 others
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newstart_MO
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Feb 2026
Springfield, MO
Oct 14, 2024 at 12:12 PM#30

Closing the loop on my own question.

Update — I was wrong in the opening post, specifically about the direction. Correcting it here rather than editing it away.

Last edited: Oct 14, 2024 at 6:12 PM
39 12RunnerRach, TrialNerd_Beth, HPLC_Greg and 36 others
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