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ForumsPharmacology & MechanismsSo the drug literally changes your brain?? That is wild — anyone have experience? Page 7

So the drug literally changes your brain?? That is wild — anyone have experience?

Dr.PulmRoch Fri, Jan 31, 2025 at 1:55 PM 49 replies 2,218 viewsPage 7 of 10
LabKate
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Apr 21, 2025 at 5:49 PM#31

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

44 17JenMemphis, pat_auckland, Dr.GastroMayo and 41 others
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PharmacoVig_BOS
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Apr 27, 2025 at 11:25 PM#32

A narrower follow-up, since the general answer is now clear:

Did your prescriber agree with that reading, and if not what was their objection?

45 18Dr.GutHealth, amsterdam_pete, LondonLisa and 42 others
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COA_Karl
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May 4, 2025 at 4:58 AM#33
LabKate said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

Happy to go further on any of that.

46 19hyun_seoul, jim_asheville, matt_MKE and 43 others
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marco_milano
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May 10, 2025 at 10:27 AM#34
LabKate said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

Last edited: May 10, 2025 at 2:27 PM
47 20tammy_FL, Dr.LipidDallas, alex_tucson and 44 others
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TomFromTexas
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May 16, 2025 at 3:53 PM#35
LabKate said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

48 21BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 45 others
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