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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsSo the drug literally changes your brain?? That is wild — anyone have experience? Page 9

So the drug literally changes your brain?? That is wild — anyone have experience?

Dr.PulmRoch Fri, Jan 31, 2025 at 1:55 PM 49 replies 2,218 viewsPage 9 of 10
cory_ATX
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Jun 22, 2025 at 9:56 PM#41
quinn_sf said:
Say what you would expect to see if you were wrong, before you look.

Pushing back on quinn_sf here. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

25 23Dr.EndoEP, GraceAZ_72, carl_compliance and 22 others
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marcus_mpls
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Jun 29, 2025 at 1:41 AM#42
quinn_sf said:
Say what you would expect to see if you were wrong, before you look.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

That is the short version; the long version is somebody else's post.

26 24oliver_london, tane_welly, Dr.PathRoch and 23 others
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Admin
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Jul 5, 2025 at 5:23 AM#43

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.

Last edited: Jul 5, 2025 at 9:23 AM
27 0RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 24 others
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PedsEndoPhilly
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Jul 11, 2025 at 9:01 AM#44

Adding the clinical framing, because it changes how the question reads. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

28 1Dr.LeslieOBGYN, MikeNYC_runner and 25 others
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LarryQC_SD
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Jul 17, 2025 at 12:35 PM#45
PedsEndoPhilly said:
Worth answering the question that was asked rather than the one behind it.

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

29 2dan_philly, MeganSA_TX, LarryQC_SD and 26 others
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