🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsHow far away are we really from an oral option — 12 month update Page 6

How far away are we really from an oral option — 12 month update

HPLC_Greg Wed, Jun 4, 2025 at 7:45 PM 47 replies 2,552 viewsPage 6 of 10
Dr.LeslieOBGYN
Member
567
2,567
May 2024
Dallas, TX
Jun 9, 2025 at 1:56 PM#26

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Jun 9, 2025 at 7:56 PM
8 6Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 5 others
Reply Quote Save Share Report
ben_calgary
Member
245
1,123
Oct 2024
Calgary, CA
Jun 10, 2025 at 2:40 AM#27
Dr.LeslieOBGYN said:
The mechanism and the magnitude are separate questions.

Adding a me-too, because a thread of one person's experience is not much use.

Last edited: Jun 10, 2025 at 8:40 AM
9 7CanadaChris, ZaraB_AL, JakeSmashed95 and 6 others
Reply Quote Save Share Report
KetoKyle
Member
678
3,456
Jul 2024
Utah
Jun 10, 2025 at 3:24 PM#28
Dr.LeslieOBGYN said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

10 8pat_auckland, Dr.GastroMayo, JakeBK_lifts and 7 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
raj_cambridge
Member
489
2,123
Jun 2024
Cambridge, MA
Jun 11, 2025 at 4:08 AM#29

Adding the numbers, since they settle part of this. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

11 9PharmHunterJen, TomTeleRx, DoseLogDan and 8 others
Reply Quote Save Share Report
HPLC_Greg
Senior Member
1,890
8,901
Feb 2024
Research Triangle, NC
Jun 11, 2025 at 4:51 PM#30

OP back with an update, since a thread like this is useless without one.

Update — I was wrong in the opening post, specifically about the direction. Correcting it here rather than editing it away.

33 6SaraMom3, Dr.MetabolicMD, RetaRick_CA and 30 others
Reply Quote Save Share Report
14567810

Similar Threads

Orforglipron Phase 3 ATTAIN-1 topline — oral non-peptide GLP-116 replies
Oral semaglutide 50mg (Rybelsus HD) — OASIS program results12 replies
Danuglipron BID dosing — Pfizer oral GLP-1 update7 replies
Oral vs injectable GLP-1: bioavailability and efficacy comparison5 replies
Orforglipron food interaction profile — no fasting requirement15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register