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ForumsOral GLP-1 AgonistsHas anyone dealt with rybelsus real-world vs clinical trial efficacy? Page 7

Has anyone dealt with rybelsus real-world vs clinical trial efficacy?

NeuroNate Sat, Oct 19, 2024 at 12:13 AM 31 replies 2,377 viewsPage 7 of 7
JenPlateau
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Oct 29, 2024 at 6:10 AM#31
NeuroNate said:
Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.

I read this differently from NeuroNate, on substance rather than tone. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

Last edited: Oct 29, 2024 at 12:10 PM
34 7HPLC_Greg, LibrarianMeg, bri_stats and 31 others
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KevinCompounds
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Oct 29, 2024 at 9:46 PM#32
NeuroNate said:
Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

Worth separating that from the trial evidence, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

35 8Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 32 others
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NicoleRaleigh
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Oct 30, 2024 at 1:22 PM#33
NeuroNate said:
Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Taking it to my next appointment.

36 9COA_Karl, MikeFit_NJ, InsuranceTom and 33 others
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VanRx_Mike
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Oct 31, 2024 at 4:57 AM#34

From the other side of the consultation, briefly. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

37 10Dr.Martinez, mike_mod, SarahChen_PharmD and 34 others
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emily_PDX
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Oct 31, 2024 at 8:32 PM#35
VanRx_Mike said:
It helps to say which part of this you are uncertain about.

Second this. Nothing to add that would improve it.

38 11PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 35 others
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