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ForumsTirzepatide (Mounjaro / Zepbound)Tirz made me a completely different person holy cow — looking for input Page 5

Tirz made me a completely different person holy cow — looking for input

roxy_nash Wed, Sep 10, 2025 at 7:43 PM 35 replies 1,765 viewsPage 5 of 7
oliver_london
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London, UK
Sep 12, 2025 at 5:56 AM#21

One thing that is still open after anna.melb_AU’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

Last edited: Sep 12, 2025 at 6:56 AM
28 3Admin, Dr.Martinez, mike_mod and 25 others
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Dr.RheumBOS
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Apr 2024
Boston, MA
Sep 12, 2025 at 2:27 PM#22
LeilaHI said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

I would rather be corrected than agreed with, if it comes to it.

27 2wei_SG, cory_ATX, lori_vegas and 24 others
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kevin_tulsa
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Tulsa, OK
Sep 12, 2025 at 10:58 PM#23
LeilaHI said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

Last edited: Sep 13, 2025 at 12:58 AM
26 1greg_boulder, quinn_sf, NurseLeah_Nash and 23 others
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ZaraB_AL
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Jan 2025
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Sep 13, 2025 at 7:29 AM#24
LeilaHI said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Thank you for spelling out the reasoning rather than just the conclusion.

25 0TrialTracker_MD, JennaRN, LabKate and 22 others
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Dr.EM_Chicago
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May 2024
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Sep 13, 2025 at 4:01 PM#25

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

24 24lisa_labSD, adam_van, Dr.SurgeonPGH and 21 others
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