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ForumsRetatrutide & Triple AgonistsWill reta make sema and tirz obsolete? Page 4

Will reta make sema and tirz obsolete?

andrew_nyc Sun, Apr 5, 2026 at 9:23 AM 33 replies 1,028 viewsPage 4 of 7
GenomicsKate
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Apr 11, 2026 at 12:24 AM#16

Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

12 10DebRD_ATL, KristenIndy, MarkLI_maint and 9 others
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PharmHunterJen
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Apr 11, 2026 at 9:41 PM#17

Clinical perspective, offered as context rather than as advice. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

Last edited: Apr 12, 2026 at 3:41 AM
13 11alex_tucson, kevin_tulsa, Dr.PainCLE and 10 others
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alex_tucson
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Apr 12, 2026 at 6:57 PM#18
PharmHunterJen said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Same experience, arrived at from the opposite direction.

14 12BrianDallas92, labquiet_amy, emily_PDX and 11 others
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SarahChen_PharmD
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Apr 13, 2026 at 4:12 PM#19
PharmHunterJen said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Adding the part of the answer the thread has not reached. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

Last edited: Apr 13, 2026 at 7:12 PM
15 13TinaHashiRN, robert_kc, dan_philly and 12 others
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Admin
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Apr 14, 2026 at 1:27 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.

37 10PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 34 others
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