🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesApoB reduction on tirzepatide — looking for input Page 7

ApoB reduction on tirzepatide — looking for input

TomTeleRx Tue, Jul 9, 2024 at 9:38 AM 34 replies 2,140 viewsPage 7 of 7
MariaRD
Member
823
4,567
Jun 2024
New Mexico
Jul 15, 2024 at 2:13 AM#31
bri_stats said:
Say what you would expect to see if you were wrong, before you look.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

Last edited: Jul 15, 2024 at 3:13 AM
35 8Dr.NutriCornell, pam_stl, wei_SG and 32 others
Reply Quote Save Share Report
Dr.AddMedPHL
Senior Member
1,234
6,234
Mar 2024
Philadelphia, PA
Jul 15, 2024 at 10:25 AM#32
bri_stats said:
Say what you would expect to see if you were wrong, before you look.

Saving this. It is the first explanation that did not require me to already understand it. Adding it to my notes with a link back to this thread.

36 9sarah_nash92, FitDadDave, RunnerRach and 33 others
Reply Quote Save Share Report
Dr.PeteFamMed
Senior Member
2,012
9,234
Jan 2024
Minneapolis, MN
Jul 15, 2024 at 6:37 PM#33

Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Last edited: Jul 15, 2024 at 7:37 PM
37 10LindaRN_retired, tommy_boulder, hyun_seoul and 34 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
Dr.EM_Chicago
Member
567
2,567
May 2024
Chicago, IL
Jul 16, 2024 at 2:49 AM#34
Dr.PeteFamMed said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.

38 11lucas_SP_BR, lisa_labSD, adam_van and 35 others
Reply Quote Save Share Report
mark_tokyo
Member
456
1,890
Jun 2024
Tokyo, JP
Jul 16, 2024 at 11:01 AM#35
Dr.PeteFamMed said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

There is a second half to this that has not been said yet. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

39 12TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 36 others
Reply Quote Save Share Report
1567

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register