🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesApoB reduction on tirzepatide — looking for input Page 6

ApoB reduction on tirzepatide — looking for input

TomTeleRx Tue, Jul 9, 2024 at 9:38 AM 34 replies 2,140 viewsPage 6 of 7
MeganSA_TX
Member
634
2,890
Jun 2024
San Antonio, TX
Jul 13, 2024 at 8:53 AM#26
Dr.SleepRoch said:
The mechanism and the magnitude are separate questions.

Mine went the same way, slower. Posting only so the count is not one.

Last edited: Jul 13, 2024 at 10:53 AM
9 7PharmD_Rodriguez, julia.endo, JessicaM_2024 and 6 others
Reply Quote Save Share Report
LondonLisa
Member
912
3,456
Mar 2024
London, UK
Jul 13, 2024 at 5:10 PM#27
Dr.SleepRoch said:
The mechanism and the magnitude are separate questions.

Coming at Dr.SleepRoch’s question from a different direction. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

Last edited: Jul 13, 2024 at 7:10 PM
10 8Dr.MetabolicMD, RetaRick_CA, JenPlateau and 7 others
Reply Quote Save Share Report
bri_stats
Member
789
3,456
May 2024
Seattle, WA
Jul 14, 2024 at 1:27 AM#28

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

11 9TomFromTexas, mike.trainer_LA, sarah_nash92 and 8 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
JessicaM_2024
Member
823
3,456
Mar 2024
Portland, OR
Jul 14, 2024 at 9:44 AM#29

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

12 10Dr.PainCLE, mike_mealprep, NicoleRaleigh and 9 others
Reply Quote Save Share Report
TomTeleRx
Member
189
678
Feb 2025
Delaware
Jul 14, 2024 at 6:01 PM#30

Reporting back.

Update, and it is the boring outcome: nothing was wrong. The measurement I was reading had moved less than its own week-to-week variation, which somebody said upthread and I did not believe.

34 7TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 31 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register