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ForumsTirzepatide (Mounjaro / Zepbound)Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism? Page 7

Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism?

robert_kc Fri, Apr 5, 2024 at 12:28 AM 49 replies 2,765 viewsPage 7 of 10
stefan_berlin
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Aug 27, 2024 at 4:09 PM#31

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Last edited: Aug 27, 2024 at 7:09 PM
18 16NeuroNate, JessicaH_TX, KevinCompounds and 15 others
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CarlaRPh_TPA
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Sep 7, 2024 at 11:23 PM#32

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

19 17ricardo_MIA, BrianDallas92, labquiet_amy and 16 others
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Dr.PulmRoch
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Sep 19, 2024 at 6:30 AM#33
stefan_berlin said:
Say what you would expect to see if you were wrong, before you look.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

Worth separating that from the pharmacology, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

I would rather be corrected than agreed with, if it comes to it.

20 18AttorneyGrant, DebRD_ATL, KristenIndy and 17 others
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DeniseRN_TPA
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Sep 30, 2024 at 1:31 PM#34
stefan_berlin said:
Say what you would expect to see if you were wrong, before you look.

That is correct as far as it goes, and here is where it stops going. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

21 19LindaRN_retired, tommy_boulder, hyun_seoul and 18 others
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Dr.ObesityMed
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Oct 11, 2024 at 8:25 PM#35
stefan_berlin said:
Say what you would expect to see if you were wrong, before you look.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Sending this to two other people who asked me the same thing last week.

22 20A1cHero_PHX, Dr.RenalNash, LipidDoc_ATL and 19 others
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