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ForumsTirzepatide (Mounjaro / Zepbound)Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism? Page 8

Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism?

robert_kc Fri, Apr 5, 2024 at 12:28 AM 49 replies 2,765 viewsPage 8 of 10
Dr.CardioMD
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Oct 23, 2024 at 3:13 AM#36

Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

23 21kim_atl_prep, sarah_TO, wendy_avl and 20 others
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Dr.NephBHM_UK
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Nov 3, 2024 at 9:54 AM#37
Dr.CardioMD said:
Start from the measurement rather than the conclusion.

Same pattern here, and in the same order.

24 22EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 21 others
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FDA_TrackerJim
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Nov 14, 2024 at 4:28 PM#38
Dr.CardioMD said:
Start from the measurement rather than the conclusion.

There is a second half to this that has not been said yet. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

25 23MikeNYC_runner and 22 others
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anders_CPH
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Nov 25, 2024 at 10:56 PM#39

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

26 24BethLabQueen, ChrisMacros, KetoKyle and 23 others
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DebRD_ATL
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Dec 7, 2024 at 5:17 AM#40

A narrower follow-up, since the general answer is now clear:

What would you measure differently if you were starting again?

48 21HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 45 others
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