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ForumsRetatrutide & Triple AgonistsRetatrutide Phase 2 dose-response analysis — need advice Page 3

Retatrutide Phase 2 dose-response analysis — need advice

SarahChen_PharmD Wed, Sep 11, 2024 at 8:40 PM 55 replies 2,123 viewsPage 3 of 11
VendorMark
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Sep 12, 2024 at 9:14 AM#11
CarlaRPh_TPA said:
Read four things before the headline number.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

28 1DebRD_ATL, KristenIndy, MarkLI_maint and 25 others
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anna.melb_AU
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Sep 12, 2024 at 12:47 PM#12
PurityPaulOR said:
The glucagon component looks paradoxical and is not.

That reframing is the part I needed. Sending this to two other people who asked me the same thing last week.

Last edited: Sep 12, 2024 at 4:47 PM
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MaxMetOK
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Sep 12, 2024 at 4:20 PM#13
CarlaRPh_TPA said:
Read four things before the headline number.

I read this differently from CarlaRPh_TPA, on substance rather than tone. I would add the less popular caveat: these trial populations under-represented several groups, older adults and the highest BMI categories among them. The results probably generalise, and "probably" should be stated as an assumption rather than dropped.

Last edited: Sep 12, 2024 at 9:20 PM
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Dr.NateNeph
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Sep 12, 2024 at 7:53 PM#14

One concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

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mike_mod
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Sep 12, 2024 at 11:26 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Thread quality here is what the rules are for. Keep it up.

Last edited: Sep 13, 2024 at 1:26 AM
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