🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGLP-1 and gluconeogenesis — what worked for you? Page 6

GLP-1 and gluconeogenesis — what worked for you?

matt_MKE Mon, Oct 20, 2025 at 10:35 AM 50 replies 1,666 viewsPage 6 of 10
robert_kc
Member
289
1,234
Oct 2024
Kansas City, MO
Dec 11, 2025 at 8:19 PM#26
DoseLogDan said:
If you are going to change something, change one thing and give it long enough to express itself.

Genuinely useful, thank you. I had the facts and not the framework.

15 13PurityPaulOR, MaxMetOK, MounjBrad and 12 others
Reply Quote Save Share Report
traveltech_sara
Member
156
678
Jan 2025
Remote, USA
Dec 18, 2025 at 3:24 PM#27

From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

16 14LarryQC_SD, wanda_boise, NurseAsh_DET and 13 others
Reply Quote Save Share Report
RickReta_CO
Member
312
1,234
Jan 2025
Colorado
Dec 25, 2025 at 10:25 AM#28
traveltech_sara said:
The mechanism and the magnitude are separate questions.

This is my experience too, for whatever a second data point is worth.

17 15hyun_seoul, jim_asheville, matt_MKE and 14 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
KarenAZ_mom
Member
567
2,567
Aug 2024
Scottsdale, AZ
Jan 1, 2026 at 5:22 AM#29
traveltech_sara said:
The mechanism and the magnitude are separate questions.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

That is the short version; the long version is somebody else's post.

18 16LibrarianMeg, bri_stats, pete_manc_UK and 15 others
Reply Quote Save Share Report
matt_MKE
Member
312
1,345
Sep 2024
Milwaukee, WI
Jan 8, 2026 at 12:15 AM#30

OP back with an update, since a thread like this is useless without one.

Following up because I said I would. I changed one thing, left everything else alone, and waited the full interval before looking. It resolved, and I cannot prove which half of that did it.

40 13DanielChem_CHI, marco_milano, pam_columbus and 37 others
Reply Quote Save Share Report
14567810

Similar Threads

SUSTAIN-6 to SELECT — the cardiovascular evidence timeline14 replies
GLP-1 and insulin resistance — HOMA-IR improvement data17 replies
Metabolic syndrome reversal criteria — how GLP-1 addresses all 55 replies
A1C target achievement rates — sema vs tirz comparison8 replies
SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design3 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register