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ForumsCardiovascular OutcomesApoB reduction on tirzepatide — looking for input Page 4

ApoB reduction on tirzepatide — looking for input

TomTeleRx Tue, Jul 9, 2024 at 9:38 AM 34 replies 2,140 viewsPage 4 of 7
NicoleRaleigh
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Jul 11, 2024 at 1:55 AM#16
sean_dublin said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This is my experience too, for whatever a second data point is worth.

Last edited: Jul 11, 2024 at 2:55 AM
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Dr.EndoIndy
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Jul 11, 2024 at 4:37 AM#17

Clinical perspective, offered as context rather than as advice. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

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hyun_seoul
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Jul 11, 2024 at 7:19 AM#18
Dr.EndoIndy said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Same pattern here, and in the same order.

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Dr.EM_Chicago
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Jul 11, 2024 at 10:01 AM#19
Dr.EndoIndy said:
If two explanations both fit, the useful question is which one predicts something the other does not.

There is a second half to this that has not been said yet. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

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mike_mod
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Jul 11, 2024 at 12:43 PM#20

Moderator note: a couple of off-topic posts removed. Report rather than reply if it drifts again.

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