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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersKidney function on semaglutide — need advice Page 6

Kidney function on semaglutide — need advice

sean_dublin Thu, May 30, 2024 at 3:16 PM 37 replies 2,704 viewsPage 6 of 8
quinn_sf
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Jul 16, 2024 at 7:01 PM#26

Following on from Dr.RheumBOS — and this may be the naive question:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

34 7tane_welly, Dr.PathRoch, mona_PHX and 31 others
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sarah_nash92
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Jul 22, 2024 at 9:10 PM#27
VendorMark said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

35 8JakeSmashed95, NauseaFreeNow, SteveThurs and 32 others
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bri_stats
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Jul 28, 2024 at 11:16 PM#28
VendorMark said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Worth separating that from renal function, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

I would rather be corrected than agreed with, if it comes to it.

Last edited: Jul 29, 2024 at 3:16 AM
36 9TomFromTexas, mike.trainer_LA, sarah_nash92 and 33 others
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Dr.ObesityMed
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Aug 4, 2024 at 1:18 AM#29
VendorMark said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

This answered a question I did not know how to ask.

37 10PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 34 others
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sean_dublin
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Aug 10, 2024 at 3:17 AM#30

Reporting back.

Update. I did go to 2.4mg in the end, and the honest report is that it bought me less than the step before it and cost me two bad weeks. Worth knowing rather than worth repeating.

9 7quinn_sf, NurseLeah_Nash, gary_naperville and 6 others
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