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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsHas anyone dealt with rybelsus real-world vs clinical trial efficacy? Page 4

Has anyone dealt with rybelsus real-world vs clinical trial efficacy?

NeuroNate Sat, Oct 19, 2024 at 12:13 AM 31 replies 2,377 viewsPage 4 of 7
mike_mealprep
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Oct 21, 2024 at 4:46 PM#16
Dr.NateNeph said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Same pattern here, and in the same order.

27 0mia_MS2, LeilaHI, marcus_mpls and 24 others
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PeptideChemSF
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Oct 21, 2024 at 9:33 PM#17
Dr.GutHealth said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Thank you for spelling out the reasoning rather than just the conclusion. I will report back once I have actually tried it.

28 1dave_SLC, FDA_TrackerJim, ricardo_MIA and 25 others
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roxy_nash
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Oct 22, 2024 at 2:20 AM#18

Adding the clinical framing, because it changes how the question reads. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

29 2tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 26 others
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emma_london
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Oct 22, 2024 at 7:07 AM#19
roxy_nash said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

This matches mine closely enough to be worth saying so out loud.

30 3JessicaM_2024, TomFromTexas, mike.trainer_LA and 27 others
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mike_mod
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Oct 22, 2024 at 11:53 AM#20

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.

2 0PurityPaulOR, MaxMetOK
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